Two-stage genome-wide methylation profiling in childhood-onset Crohn's Disease implicates epigenetic alterations at the VMP1/MIR21 and HLA loci

As a result of technological and analytical advances, genome-wide characterization of key epigenetic alterations is now feasible in complex diseases. We hypothesized that this may provide important insights into gene-environmental interactions in Crohn's disease (CD) and is especially pertinent...

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Bibliographic Details
Main Authors: Adams, A, Kennedy, N, Hansen, R, Ventham, N, OʼLeary, K, Drummond, H, Noble, C, El-Omar, E, Russell, R, Wilson, D, Nimmo, E, Hold, G, Satsangi, J
Format: Journal article
Language:English
Published: Oxford University Press 2014