REACTION OF RUPPERT REAGENT (TMS-CF3) WITH OXAZOLIDINONES - SYNTHESIS OF PROTECTED ALPHA-AMINO TRIFLUOROMETHYLKETONES

(Trifluoromethyl)trimethylsilane adds to α-amino acid derived oxazolidin-5-ones in excellent yields. The adducts can be converted into protected α-amino trifluoromethylketones by acid hydrolysis. © 1995 Pergamon Elsevier Science Ltd.

Bibliographic Details
Main Authors: Walter, M, Adlington, R, Baldwin, J, Chuhan, J, Schofield, C
Format: Journal article
Published: 1995