Modelling monogenic diabetes mutations using authentic human beta cell models
<p>Genome-wide association studies have identified over 400 loci associated with risk for type 2 diabetes (T2D), a large proportion are associated with pancreatic islet dysfunction. The parallel emergence of genome editing technology such as CRISPR/Cas9, alongside the ability to derive endocri...
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| Format: | Thesis |
| Language: | English |
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2020
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