Modelling monogenic diabetes mutations using authentic human beta cell models

<p>Genome-wide association studies have identified over 400 loci associated with risk for type 2 diabetes (T2D), a large proportion are associated with pancreatic islet dysfunction. The parallel emergence of genome editing technology such as CRISPR/Cas9, alongside the ability to derive endocri...

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Detalles Bibliográficos
Autor Principal: Duff, C
Outros autores: Hastoy, B
Formato: Thesis
Idioma:English
Publicado: 2020
Subjects: