Expression of bcl-2 protein predicts efficacy of adjuvant treatments in operable node-positive breast cancer.

The proto-oncogene bcl-2 encodes a protein that inhibits apoptosis, a common mechanism of cell death caused by hormone and chemotherapy. We have analyzed bcl-2 protein expression by immuno-cytochemistry in primary node-positive breast cancers in two groups of patients (for a total of 180 cases). One...

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Bibliographic Details
Main Authors: Gasparini, G, Barbareschi, M, Doglioni, C, Palma, P, Mauri, F, Boracchi, P, Bevilacqua, P, Caffo, O, Morelli, L, Verderio, P
Format: Journal article
Language:English
Published: 1995