Pharmacological disruption of the outer limiting membrane leads to increased retinal integration of transplanted photoreceptor precursors.

Pharmacological disruption of the outer limiting membrane leads to increased retinal integration of transplanted photoreceptor precursors.

Retinal degeneration is the leading cause of untreatable blindness in the developed world. Cell transplantation strategies provide a novel therapeutic approach to repair the retina and restore sight. Previously, we have shown that photoreceptor precursor cells can integrate and form functional photo...

書誌詳細
主要な著者:	West, E, Pearson, R, Tschernutter, M, Sowden, J, Maclaren, R, Ali, R
フォーマット:	Journal article
言語:	English
出版事項:	2008

類似資料

Retinal repair by transplantation of photoreceptor precursors.
著者:: Maclaren, R, 等
出版事項: (2006)

Targeted disruption of outer limiting membrane junctional proteins (Crb1 and ZO-1) increases integration of transplanted photoreceptor precursors into the adult wild-type and degenerating retina.
著者:: Pearson, R, 等
出版事項: (2010)

Targeted Disruption of Outer Limiting Membrane Junctional Proteins (Crb1 and ZO-1) Increases Integration of Transplanted Photoreceptor Precursors into the Adult Wild-Type and Degenerating Retina
著者:: R. A. Pearson, 等
出版事項: (2010-04-01)

Overexpression of developmentally regulated neurotrophins in the adult mouse retina to facilitate integration of transplanted photoreceptor precursor cells
著者:: West, E, 等
出版事項: (2008)

Outer segment formation of transplanted photoreceptor precursor cells.
著者:: Dominic Eberle, 等
出版事項: (2012-01-01)

Manipulation of the recipient retinal environment by ectopic expression of neurotrophic growth factors can improve transplanted photoreceptor integration and survival.
著者:: West, E, 等
出版事項: (2012)

Immature neural retinal cells integrate and differentiate into photoreceptors when transplanted into the mouse subreitnal space at post-natal day 1
著者:: Maclaren, R, 等
出版事項: (2005)

Cell transplantation strategies for retinal repair.
著者:: West, E, 等
出版事項: (2009)

Manipulation of the Recipient Retinal Environment by Ectopic Expression of Neurotrophic Growth Factors Can Improve Transplanted Photoreceptor Integration and Survival
著者:: E. L. West, 等
出版事項: (2012-05-01)

Donor and host photoreceptors engage in material transfer following transplantation of post-mitotic photoreceptor precursors
著者:: R. A. Pearson, 等
出版事項: (2016-10-01)

Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion
著者:: Singh, M, 等
出版事項: (2016)

Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion
著者:: Mandeep S. Singh, 等
出版事項: (2016-11-01)

Long-term survival of photoreceptors transplanted into the adult murine neural retina requires immune modulation.
著者:: West, E, 等
出版事項: (2010)

Cone fusion confusion in photoreceptor transplantation
著者:: MacLaren, R
出版事項: (2017)

Reversal of end-stage retinal degeneration and restoration of visual function by photoreceptor transplantation.
著者:: Singh, MS, 等
出版事項: (2013)

External Limiting Membrane, Photoreceptor Ellipsoid Zone Disruption, and Retinal Pigment Epithelium Alterations in Diabetic Retinopathy
著者:: Nibha Mishra, 等
出版事項: (2022-07-01)

Deletion of prominin-1 in mice results in disrupted photoreceptor outer segment protein homeostasis
著者:: Yu-Shu Xiao, 等
出版事項: (2021-09-01)

Effective protection of photoreceptors using an inflammation-responsive hydrogel to attenuate outer retinal degeneration
著者:: Hyerim Kim, 等
出版事項: (2023-12-01)

Quantitative Assessment of Outer Retinal Layer and Photoreceptor Outer Segment Layer and Their Relation to Visual Acuity in Diabetic Macular Edema
著者:: Ahmed Hosni Abd Elhamid
出版事項: (2019-01-01)

Transplantation of adult mouse iPS cell-derived photoreceptor precursors restores retinal structure and function in degenerative mice.
著者:: Budd A Tucker, 等
出版事項: (2011-04-01)

CRX haploinsufficiency compromises photoreceptor precursor translocation and differentiation in human retinal organoids
著者:: Deng Pan, 等
出版事項: (2023-12-01)

Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors
著者:: Anai Gonzalez-Cordero, 等
出版事項: (2017-09-01)

Photoreceptor Outer Segment on Internal Limiting Membrane after Macular Hole Surgery: Implications for Pathogenesis
著者:: Michael E. Grinton, 等
出版事項: (2015-09-01)

The Formation and Renewal of Photoreceptor Outer Segments
著者:: Jingjin Xu, 等
出版事項: (2024-08-01)

CYLD Maintains Retinal Homeostasis by Deubiquitinating ENKD1 and Promoting the Phagocytosis of Photoreceptor Outer Segments
著者:: Song Yang, 等
出版事項: (2024-12-01)

Correction: Transplantation of Adult Mouse iPS Cell-Derived Photoreceptor Precursors Restores Retinal Structure and Function in Degenerative Mice.
著者:: Budd A Tucker, 等
出版事項: (2015-01-01)

Induced pluripotent stem cells and derivative photoreceptor precursors as therapeutic cells for retinal degenerations
著者:: Rupendra Shrestha, 等
出版事項: (2020-01-01)

Induction of rod versus cone photoreceptor-specific progenitors from retinal precursor cells
著者:: Saeed Khalili, 等
出版事項: (2018-12-01)

Kif17 phosphorylation regulates photoreceptor outer segment turnover
著者:: Tylor R. Lewis, 等
出版事項: (2018-11-01)

Photoreceptor Inner and Outer Segment Junction Reflectivity after Vitrectomy for Macula-Off Rhegmatogenous Retinal Detachment
著者:: Jakub J. Kaluzny, 等
出版事項: (2015-01-01)

HBEGF-TNF induce a complex outer retinal pathology with photoreceptor cell extrusion in human organoids
著者:: Manuela Völkner, 等
出版事項: (2022-10-01)

Correlation between brain volume and retinal photoreceptor outer segment volume in normal aging and neurodegenerative diseases.
著者:: Atsuro Uchida, 等
出版事項: (2020-01-01)

cGMP-grade human iPSC-derived retinal photoreceptor precursor cells rescue cone photoreceptor damage in non-human primates
著者:: Swathi Lingam, 等
出版事項: (2021-08-01)

AAV-Mediated Expression of Secreted Human Ciliary Neurotropic Factor (hCNTF) Leads to Long-Term Preservation of Cone Photoreceptors in an Autosomal Recessive Model of Retinitis Pigmentosa
著者:: Lipinski, D, 等
出版事項: (2013)

Inner retinal thickening affects microperimetry thresholds in the presence of photoreceptor thinning in patients with RPGR retinitis pigmentosa
著者:: Jolly, JK, 等
出版事項: (2020)

Deep Learning-Assisted Measurements of Photoreceptor Ellipsoid Zone Area and Outer Segment Volume as Biomarkers for Retinitis Pigmentosa
著者:: Yi-Zhong Wang, 等
出版事項: (2023-12-01)

MERTK-Dependent Ensheathment of Photoreceptor Outer Segments by Human Pluripotent Stem Cell-Derived Retinal Pigment Epithelium
著者:: Seba Almedawar, 等
出版事項: (2020-03-01)

Cone photoreceptor neuroprotection conferred by CNTF in a novel in vivo model of battlefield retinal laser injury.
著者:: Aslam, SA, 等
出版事項: (2013)

Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa
著者:: Budd A Tucker, 等
出版事項: (2013-08-01)

Retinal Thickening and Photoreceptor Loss in HIV Eyes without Retinitis.
著者:: Cheryl A Arcinue, 等
出版事項: (2015-01-01)