Pharmacological disruption of the outer limiting membrane leads to increased retinal integration of transplanted photoreceptor precursors.
Retinal degeneration is the leading cause of untreatable blindness in the developed world. Cell transplantation strategies provide a novel therapeutic approach to repair the retina and restore sight. Previously, we have shown that photoreceptor precursor cells can integrate and form functional photo...
Asıl Yazarlar: | West, E, Pearson, R, Tschernutter, M, Sowden, J, Maclaren, R, Ali, R |
---|---|
Materyal Türü: | Journal article |
Dil: | English |
Baskı/Yayın Bilgisi: |
2008
|
Benzer Materyaller
-
Retinal repair by transplantation of photoreceptor precursors.
Yazar:: Maclaren, R, ve diğerleri
Baskı/Yayın Bilgisi: (2006) -
Targeted disruption of outer limiting membrane junctional proteins (Crb1 and ZO-1) increases integration of transplanted photoreceptor precursors into the adult wild-type and degenerating retina.
Yazar:: Pearson, R, ve diğerleri
Baskı/Yayın Bilgisi: (2010) -
Targeted Disruption of Outer Limiting Membrane Junctional Proteins (Crb1 and ZO-1) Increases Integration of Transplanted Photoreceptor Precursors into the Adult Wild-Type and Degenerating Retina
Yazar:: R. A. Pearson, ve diğerleri
Baskı/Yayın Bilgisi: (2010-04-01) -
Overexpression of developmentally regulated neurotrophins in the adult mouse retina to facilitate integration of transplanted photoreceptor precursor cells
Yazar:: West, E, ve diğerleri
Baskı/Yayın Bilgisi: (2008) -
Outer segment formation of transplanted photoreceptor precursor cells.
Yazar:: Dominic Eberle, ve diğerleri
Baskı/Yayın Bilgisi: (2012-01-01)