The microRNA-30 family targets DLL4 to modulate endothelial cell behavior during angiogenesis.

The microRNA-30 family targets DLL4 to modulate endothelial cell behavior during angiogenesis.

Delta-like 4 (DLL4), a membrane-bound ligand belonging to the Notch signaling family, plays a fundamental role in vascular development and angiogenesis. We identified a conserved microRNA family, miR-30, which targets DLL4. Overexpression of miR-30b in endothelial cells led to increased vessel numbe...

Полное описание

Библиографические подробности
Главные авторы:	Bridge, G, Monteiro, R, Henderson, S, Emuss, V, Lagos, D, Georgopoulou, D, Patient, R, Boshoff, C
Формат:	Journal article
Язык:	English
Опубликовано:	2012

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