Nucleophosmin and p14ARF mediated regulation of p53

Nucleophosmin and p14ARF mediated regulation of p53

<p>Tumour initiation and progression occur due to oncogenic mutations that also contribute to therapeutic resistance in many human tumours. Mutations activating the "PI3K/AKT" signalling pathway and inactivating the "<em>TP53</em>" tumour suppressor gene are com...

書目詳細資料
主要作者:	Abraham, A
其他作者:	O'Neill, E
格式:	Thesis
語言:	English
出版:	2015
主題:	Oncology

相似書籍

p53-Induced Apoptosis Occurs in the Absence of p14ARF in Malignant Pleural Mesothelioma
由: Sally Hopkins-Donaldson, et al.
出版: (2006-07-01)

The complex role of SIRT7 in p53 stabilization: nucleophosmin joins the debate
由: Poonam Kumari, et al.
出版: (2021-05-01)

Oncomir miR-125b suppresses p14(ARF) to modulate p53-dependent and p53-independent apoptosis in prostate cancer.
由: Sumaira Amir, et al.
出版: (2013-01-01)

The p53 response: a new mitochondrial role for cofactor strap
由: Maniam, S
出版: (2013)

The ubiquitin ligase TRIM21 regulates mutant p53 accumulation and gain of function in cancer
由: Juan Liu, et al.
出版: (2023-03-01)

Overexpression of CCDC69 activates p14ARF/MDM2/p53 pathway and confers cisplatin sensitivity
由: Long Cui, et al.
出版: (2019-01-01)

p14ARF induces the relocation of HDM2 and p53 to extranucleolar sites that are targeted by PML bodies and proteasomes
由: Klein George, et al.
出版: (2003-03-01)

Nucleophosmin Protein Dephosphorylation by DUSP3 Is a Fine-Tuning Regulator of p53 Signaling to Maintain Genomic Stability
由: Lilian C. Russo, et al.
出版: (2021-03-01)

MDM2-mediated degradation of p14ARF: a novel mechanism to control ARF levels in cancer cells.
由: Maria Vivo, et al.
出版: (2015-01-01)

The Senescence Markers p16INK4A, p14ARF/p19ARF, and p21 in Organ Development and Homeostasis
由: Kay-Dietrich Wagner, et al.
出版: (2022-06-01)

Regulation of p14<sup>ARF </sup>expression by miR-24: a potential mechanism compromising the p53 response during retinoblastoma development
由: To Kwong-Him, et al.
出版: (2012-02-01)

p19(ARF) /p14(ARF) controls oncogenic functions of signal transducer and activator of transcription 3 in hepatocellular carcinoma.
由: Schneller, D, et al.
出版: (2011)

Correlation between promoter methylation of <it>p14<sup>ARF</sup></it>, <it>TMS1/ASC</it>, and <it>DAPK</it>, and <it>p53 </it>mutation with prognosis in cholangiocarcinoma
由: Xiaofang Liu, et al.
出版: (2012-01-01)

The expression level of ARF and p53 in AML patients, and their relation to patients' outcome
由: Reem Nabil, et al.
出版: (2023-03-01)

Side-stepping the guardian of the genome: current cancer therapeutics targeting mutant p53
由: Iulianna C. Taritsa, et al.
出版: (2025-01-01)

Annexin/S100A Protein Family Regulation through p14ARF-p53 Activation: A Role in Cell Survival and Predicting Treatment Outcomes in Breast Cancer.
由: Diana Hatoum, et al.
出版: (2017-01-01)

Crosstalk between E2F3 and p19ARF/p53 in the regulation of cell cycle progression and tumorigenesis
由: Aslanian, Aaron Spencer
出版: (2006)

Increased p53 expression induced by APR-246 reprograms tumor-associated macrophages to augment immune checkpoint blockade
由: Arnab Ghosh, et al.
出版: (2022-09-01)

Xanthorrhizol Induces Apoptosis Via the Up-regulation of Bax and p53 in HeLa Cells
由: Ismail, Norzila, et al.
出版: (2005)

Human papillomavirus 16 oncoprotein E7 stimulates UBF1-mediated rDNA gene transcription, inhibiting a p53-independent activity of p14ARF.
由: Isabelle Dichamp, et al.
出版: (2014-01-01)

A distinct p53 target gene set predicts for response to the selective p53–HDM2 inhibitor NVP-CGM097
由: Sébastien Jeay, et al.
出版: (2015-05-01)

Unmasking a new prognostic marker and therapeutic target from the GDNF-RET/PIT1/p14ARF/p53 pathway in acromegalyResearch in context
由: Miguel Chenlo, et al.
出版: (2019-05-01)

A preliminary study of p53 oncogene expression in lung samples
由: Rahman, Md.Tahminur
出版: (2003)

Prognostic value of p14ARF expression in diffuse large B cell lymphoma
由: М. V. Sarpova, et al.
出版: (2024-04-01)

Molecular genetic analysis in B-cell Lymphomas : a focus on the p53 pathway and p16INK4a
由: Zainuddin, Norafiza
出版: (2010)

Mimicking p14ARF phosphorylation influences its ability to restrain cell proliferation.
由: Maria Vivo, et al.
出版: (2013-01-01)

Genetic variation in MDM2 and p14ARF and susceptibility to salivary gland carcinoma.
由: Lei Jin, et al.
出版: (2012-01-01)

Reactivity of p53 protein in canine transmissible venereal tumor Reatividade da proteína P53 no tumor venéreo transmissível canino
由: J.V. Moro, et al.
出版: (2010-04-01)

p19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathways.
由: Karen S Kelly-Spratt, et al.
出版: (2004-08-01)

Tissue-specific interactions between oncogenic K-ras and the p19A̳r̳f̳_p53 pathway determine susceptibility to transformation
由: Young, Nathan Price
出版: (2010)

NSC348884 cytotoxicity is not mediated by inhibition of nucleophosmin oligomerization
由: Markéta Šašinková, et al.
出版: (2021-01-01)

The role of p53 in hypoxia-induced apoptosis
由: Poole, R
出版: (2010)

SIVA-1 enhances acquired chemotherapeutic drug resistance of gastric cancer in vivo by regulating the ARF/MDM2/p53 pathway
由: Xiao-Tong Wang, et al.
出版: (2024-01-01)

Correction: Mimicking p14ARF Phosphorylation Influences Its Ability to Restrain Cell Proliferation.
由: Maria Vivo, et al.
出版: (2013-01-01)

The identification and analysis of molecular biomarkers in the p53 tumour suppressor pathway that affect cancer progression in humans
由: Grawenda, A, et al.
出版: (2013)

p14ARF forms meso-scale assemblies upon phase separation with NPM1
由: Eric Gibbs, et al.
出版: (2024-11-01)

Correction: Mimicking p14ARF Phosphorylation Influences Its Ability to Restrain Cell Proliferation
出版: (2013-01-01)

P14/ARF-Positive Malignant Pleural Mesothelioma: A Phenotype With Distinct Immune Microenvironment
由: Federica Pezzuto, et al.
出版: (2021-03-01)

Gemcitabine therapeutically disrupts essential SIRT1-mediated p53 repression in atypical teratoid/rhabdoid tumors
由: Dennis S. Metselaar, et al.
出版: (2024-09-01)

Decreased Mdm2 expression inhibits tumor development and extends survival independent of Arf and dependent on p53.
由: Christine M Eischen, et al.
出版: (2012-01-01)