Nucleophosmin and p14ARF mediated regulation of p53

<p>Tumour initiation and progression occur due to oncogenic mutations that also contribute to therapeutic resistance in many human tumours. Mutations activating the "PI3K/AKT" signalling pathway and inactivating the "<em>TP53</em>" tumour suppressor gene are com...

Полное описание

Библиографические подробности
Главный автор: Abraham, A
Другие авторы: O'Neill, E
Формат: Диссертация
Язык:English
Опубликовано: 2015
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