Unraveling adaptive evolution: how a single point mutation affects the protein coregulation network.

Understanding the mechanisms of evolution requires identification of the molecular basis of the multiple (pleiotropic) effects of specific adaptive mutations. We have characterized the pleiotropic effects on protein levels of an adaptive single-base pair substitution in the coding sequence of a sign...

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Bibliographic Details
Main Authors: Knight, C, Zitzmann, N, Prabhakar, S, Antrobus, R, Dwek, R, Hebestreit, H, Rainey, P
Format: Journal article
Language:English
Published: Nature Publishing Group 2012