Exploring the regulation of myofilament function in the heart using experimental and computational approaches
<p>Precise spatio-temporal control of 3’,5’-cyclic adenosine monophosphate (cAMP) and protein kinase A (PKA) is essential for normal cardiac function. Dysregulation of cAMP-dependent, PKA-mediated phosphorylation of myofilament proteins, such as troponin I (TNI) and myosin binding protein C (M...
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| Format: | Thesis |
| Language: | English |
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2024
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