Nuclear and membrane expression of the angiogenesis regulator delta-like ligand 4 (DLL4) in normal and malignant human tissues.

AIMS: Delta-like ligand 4 (DLL4) is one of five known Notch ligands in mammals and interacts predominantly with Notch 1. DLL4 is induced by vascular endothelial growth factor (VEGF) and acts downstream of VEGF as a 'brake' on VEGF-induced vessel growth, forming an autoregulatory negative...

Повний опис

Бібліографічні деталі
Автори: Martinez, J, Müller, M, Turley, H, Steers, G, Choteau, L, Li, J, Sainson, R, Harris, A, Pezzella, F, Gatter, K
Формат: Journal article
Мова:English
Опубліковано: 2009