Asymmetric synthesis of (-)-(S,S)-homaline

The asymmetric synthesis of (-)-(S,S)-homaline was achieved in 8 steps from commercially available starting materials using the diastereoselective conjugate addition of the novel lithium amide reagent lithium (R)-N-(3-chloropropyl)-N-(α-methyl-p-methoxybenzyl)amide to methyl cinnamate to install the...

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Autori principali: Davies, S, Lee, J, Roberts, P, Stonehouse, J, Thomson, J
Natura: Journal article
Lingua:English
Pubblicazione: 2012