Interrogation of functional miRNA–target interactions by CRISPR/Cas9 genome engineering
Post-transcriptional silencing by microRNAs (miRNAs) is a critical constituent of eukaryotic gene regulation. miRNAs are short (~22nt) noncoding RNAs capable of specifically targeting the miRNA-induced-silencing-complex (miRISC) to transcripts bearing a complementary miRNA response element (MRE). Al...
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Book section |
| Language: | English |
| Published: |
Humana Press
2017
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