Interrogation of functional miRNA–target interactions by CRISPR/Cas9 genome engineering
Post-transcriptional silencing by microRNAs (miRNAs) is a critical constituent of eukaryotic gene regulation. miRNAs are short (~22nt) noncoding RNAs capable of specifically targeting the miRNA-induced-silencing-complex (miRISC) to transcripts bearing a complementary miRNA response element (MRE). Al...
Κύριοι συγγραφείς: | , , |
---|---|
Άλλοι συγγραφείς: | |
Μορφή: | Book section |
Γλώσσα: | English |
Έκδοση: |
Humana Press
2017
|