The dynamics of signal triggering in a gp130-receptor complex.

gp130 is a shared signal-transducing membrane-associated receptor for several hematopoietic cytokines. The 30 A resolution cryo-electron microscopy (cryo-EM) structure of the Interleukin 11(IL-11)-IL-11 Receptor-gp130 extracellular complex reveals the architecture and dynamics of this gp130-containi...

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Bibliographic Details
Main Authors: Matadeen, R, Hon, W, Heath, J, Jones, E, Fuller, S
Format: Journal article
Language:English
Published: 2007