Chiral phosphorothioate analogues of B-DNA. The crystal structure of Rp-d[Gp(S)CpGp(S)CpGp(S)C].

The compound Rp-d[Gp(S)CpGp(S)CpGp(S)C], an analogue of the deoxyoligomer d(G-C)3, crystallizes in space group P2(1)2(1)2(1) with a = 34.90 A, b = 39.15 A and c = 20.64 A. The structure, which is not isomorphous with any previously determined deoxyoligonucleotide, was refined to an R factor of 14.5%...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Cruse, W, Salisbury, SA, Brown, T, Cosstick, R, Eckstein, F, Kennard, O
Format: Journal article
Sprache:English
Veröffentlicht: 1986