Characterization of within-host Plasmodium falciparum diversity using next-generation sequence data.

Our understanding of the composition of multi-clonal malarial infections and the epidemiological factors which shape their diversity remain poorly understood. Traditionally within-host diversity has been defined in terms of the multiplicity of infection (MOI) derived by PCR-based genotyping. Massive...

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Detalhes bibliográficos
Principais autores: Auburn, S, Campino, S, Miotto, O, Djimde, A, Zongo, I, Manske, M, Maslen, G, Mangano, V, Alcock, D, MacInnis, B, Rockett, K, Clark, T, Doumbo, O, Ouédraogo, J, Kwiatkowski, D
Formato: Journal article
Idioma:English
Publicado em: 2012