Evaluation of splenic accumulation and colocalization of immature reticulocytes and Plasmodium vivax in asymptomatic malaria: A prospective human splenectomy study

<br><strong>Background<br></strong> A very large biomass of intact asexual-stage malaria parasites accumulates in the spleen of asymptomatic human individuals infected with Plasmodium vivax. The mechanisms underlying this intense tropism are not clear. We hypothesised that im...

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Main Authors: Kho, S, Qotrunnada, L, Leonardo, L, Andries, B, Wardani, PAI, Fricot, A, Henry, B, Hardy, D, Margyaningsih, NI, Apriyanti, D, Puspitasari, AM, Prayoga, P, Trianty, L, Kenangalem, E, Chretien, F, Brousse, V, Safeukui, I, del Portillo, HA, Fernandez-Becerra, C, Meibalan, E, Marti, M, Price, RN, Woodberry, T, Ndour, PA, Russell, BM, Yeo, TW, Minigo, G, Noviyanti, R, Poespoprodjo, JR, Siregar, NC, Buffet, PA, Anstey, NM
Format: Journal article
Language:English
Published: Public Library of Science 2021