Genetic lineage tracing in clonal haematopoiesis and myeloproliferative neoplasms
Clonal haematopoiesis (CH) is a common age-related condition in which somatic mutations accumulate in haematopoietic stem and progenitor cells (HSPCs), leading to the clonal expansion of mutated cells. This process has been causatively linked with atherosclerotic cardiovascular disease and related c...
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Format: | Thesis |
Language: | English |
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2023
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