Dietary Supplementation with Homoarginine Preserves Cardiac Function in a Murine Model of Post-Myocardial Infarction Heart Failure

Dietary Supplementation with Homoarginine Preserves Cardiac Function in a Murine Model of Post-Myocardial Infarction Heart Failure

Low plasma homoarginine (HA) is an emerging biomarker for cardiovascular disease and an independent predictor of mortality in patients with heart failure. Plasma levels appear to reflect cardiac dysfunction, positively correlating with ejection fraction and inversely with circulating brain natriuret...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Atzler, D, McAndrew, D, Cordts, K, Schneider, J, Zervou, S, Schwedhelm, E, Neubauer, S, Lygate, C
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	American Heart Association 2017

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gan: McAndrew, DJ, et al.
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Influence of homoarginine on creatine accumulation and biosynthesis in the mouse
gan: Lygate, CA, et al.
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Impaired cardiac contractile function in AGAT knockout mice devoid of creatine is rescued by homoarginine but not creatine
gan: Faller, K, et al.
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gan: Cao, F, et al.
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gan: Murray, A, et al.
Cyhoeddwyd: (2003)

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gan: Nitz, K, et al.
Cyhoeddwyd: (2022)

Myocardial creatine levels do not influence response to acute oxidative stress in isolated perfused heart
gan: Aksentijević, D, et al.
Cyhoeddwyd: (2014)

Refinement of analgesia following thoracotomy and experimental myocardial infarction using the Mouse Grimace Scale.
gan: Faller, K, et al.
Cyhoeddwyd: (2014)

Ribose supplementation alone or with elevated creatine does not preserve high energy nucleotides or cardiac function in the failing mouse heart
gan: Faller, K, et al.
Cyhoeddwyd: (2013)

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gan: Murray, A, et al.
Cyhoeddwyd: (2002)

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gan: Zervou, S, et al.
Cyhoeddwyd: (2021)

Surgical models of hypertrophy and heart failure: Myocardial infarction and transverse aortic constriction
gan: Lygate, C
Cyhoeddwyd: (2006)

Age-dependent decline in cardiac function in guanidinoacetate-N-methyltransferase knockout mice
gan: Aksentijević, D, et al.
Cyhoeddwyd: (2019)

Investigating cardiac energetics in heart failure.
gan: Lygate, C, et al.
Cyhoeddwyd: (2013)

Investigating cardiac energetics in heart failure
gan: Lygate, C, et al.
Cyhoeddwyd: (2013)

Cardiac troponins: from myocardial infarction to chronic disease
gan: Park, KC, et al.
Cyhoeddwyd: (2017)

Over-expression of mitochondrial creatine kinase in the murine heart improves functional recovery and protects against injury following ischaemia-reperfusion
gan: Whittington, H, et al.
Cyhoeddwyd: (2018)

Synergistic effect on cardiac energetics by targeting the creatine kinase system: in vivo application of high-resolution 31P-CMRS in the mouse
gan: Maguire, ML, et al.
Cyhoeddwyd: (2023)

Apelin-13 infusion salvages the peri-infarct region to preserve cardiac function after severe myocardial injury
gan: Chung, W-J, et al.
Cyhoeddwyd: (2016)

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gan: Lygate, C, et al.
Cyhoeddwyd: (2011)

Serial 3D echocardiograhy of postinfarct remodeling in the mouse model of myocardial infarction
gan: Dawson, D, et al.
Cyhoeddwyd: (2004)

Plasma catecholamines in patients with acute myocardial infarction and in cardiac arrest.
gan: Little, R, et al.
Cyhoeddwyd: (1985)

Characterisation of the development of cardiac lymphatic vessels and their response to myocardial infarction
gan: Norman, S
Cyhoeddwyd: (2017)

Moderate elevation of intracellular creatine by targeting the creatine transporter protects mice from acute myocardial infarction.
gan: Lygate, C, et al.
Cyhoeddwyd: (2012)

Regional biochemical remodeling in non-infarcted tissue of rat heart post-myocardial infarction.
gan: Laser, A, et al.
Cyhoeddwyd: (1996)

Inhibition of myocardial cathepsin-L release during reperfusion following myocardial infarction improves cardiac function and reduces infarct size
gan: He, W, et al.
Cyhoeddwyd: (2021)

Novel insights into LV remodeling after murine myocardial infarction by in vivo magnetic resonance tissue velocity mapping
gan: Wiesmann, F, et al.
Cyhoeddwyd: (2004)

Novel insights into LV remodeling after murine myocardial infarction by in vivo magnetic resonance tissue velocity mapping.
gan: Wiesmann, F, et al.
Cyhoeddwyd: (2004)

Embolic myocardial infarction in atrial fibrillation: multiple territory injury revealed by cardiac magnetic resonance.
gan: Dall'Armellina, E, et al.
Cyhoeddwyd: (2010)

Fibulin-3 is necessary to prevent cardiac rupture following myocardial infarction
gan: Murtha, LA, et al.
Cyhoeddwyd: (2023)

Cardiac conduction system regeneration prevents arrhythmias after myocardial infarction
gan: Sayers, JR, et al.
Cyhoeddwyd: (2025)

The cardiac lymphatic system stimulates resolution of inflammation following myocardial infarction
gan: Vieira, J, et al.
Cyhoeddwyd: (2018)

Mitochondrial abnormalities in chronically infarcted rat heart
gan: Murray, A, et al.
Cyhoeddwyd: (2004)

The creatine kinase system as a therapeutic target for myocardial ischaemia-reperfusion injury
gan: Cao, F, et al.
Cyhoeddwyd: (2018)

Myocardial infarction causes inflammation and leukocyte recruitment at remote sites in the myocardium and in the renal glomerulus.
gan: Ruparelia, N, et al.
Cyhoeddwyd: (2013)

Myocardial infarction causes inflammation and leukocyte recruitment at remote sites in the myocardium and in the renal glomerulus
gan: Ruparelia, N, et al.
Cyhoeddwyd: (2013)

MYOCARDIAL INFARCTION CAUSES INFLAMMATION AND LEUKOCYTE RECRUITMENT AT REMOTE SITES IN THE MYOCARDIUM AND IN THE RENAL GLOMERULUS
gan: Ruparelia, N, et al.
Cyhoeddwyd: (2013)

The PPARgamma-activator rosiglitazone does not alter remodeling but increases mortality in rats post-myocardial infarction.
gan: Lygate, C, et al.
Cyhoeddwyd: (2003)

MLP accumulation and remodelling in the infarcted rat heart.
gan: Wilding, JR, et al.
Cyhoeddwyd: (2006)

Heart rate reduction by zatebradine reduces infarct size and mortality but promotes remodeling in rats with experimental myocardial infarction.
gan: Hu, K, et al.
Cyhoeddwyd: (2004)