The use of placebo in a trial of rectal artesunate as initial treatment for severe malaria patients en route to referral clinics: ethical issues

Placebo-controlled trials are controversial when individuals might be denied existing beneficial medical interventions. In the case of malaria, most patients die in rural villages without healthcare facilities. An artesunate suppository that can be given by minimally skilled persons might be of valu...

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Bibliographic Details
Main Authors: Kitua, A, Folb, P, Warsame, M, Binka, F, Faiz, A, Ribeiro, I, Peto, T, Gyapong, J, Yunus, E, Rahman, R, Baiden, F, Clerk, C, Mrango, Z, Makasi, C, Kimbute, O, Hossain, A, Samad, R, Gomes, M
Format: Journal article
Published: BMJ Publishing Group 2010