HIF-1 and HIF-2: working alone or together in hypoxia?

Erythropoietin (EPO) is the hormonal regulator of red cell production and provided the paradigm for oxygen-regulated gene expression that led to the discovery of hypoxia-inducible factor (HIF). In this issue of the JCI, Rankin and colleagues show, using targeted gene inactivation, that induction of...

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Detalhes bibliográficos
Autor principal: Ratcliffe, P
Formato: Journal article
Idioma:English
Publicado em: 2007