The role of germinal centers for antiviral B cell responses.
Germinal centers (GCs) are crucially involved in T cell-dependent B cell responses. B cells rapidly proliferate within GCs and their Ig variable region genes undergo hypermutation. Cognate T helper cells and antigen presented in native form on follicular dendritic cells (FDCs) select B cells express...
প্রধান লেখক: | |
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বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
1998
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