The role of germinal centers for antiviral B cell responses.

Germinal centers (GCs) are crucially involved in T cell-dependent B cell responses. B cells rapidly proliferate within GCs and their Ig variable region genes undergo hypermutation. Cognate T helper cells and antigen presented in native form on follicular dendritic cells (FDCs) select B cells express...

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Tác giả chính: Bachmann, M
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 1998