The role of germinal centers for antiviral B cell responses.
Germinal centers (GCs) are crucially involved in T cell-dependent B cell responses. B cells rapidly proliferate within GCs and their Ig variable region genes undergo hypermutation. Cognate T helper cells and antigen presented in native form on follicular dendritic cells (FDCs) select B cells express...
Tác giả chính: | |
---|---|
Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
1998
|