Effect of a 2-week interruption in methotrexate treatment versus continued treatment on COVID-19 booster vaccine immunity in adults with inflammatory conditions (VROOM study): a randomised, open label, superiority trial

Effect of a 2-week interruption in methotrexate treatment versus continued treatment on COVID-19 booster vaccine immunity in adults with inflammatory conditions (VROOM study): a randomised, open label, superiority trial

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<strong>Background<br></strong> Immunosuppressive treatments inhibit vaccine-induced immunity against SARS-CoV-2. We evaluated whether a 2-week interruption of methotrexate treatment immediately after the COVID-19 vaccine booster improved antibody responses against the S1 receptor-...

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Bibliographic Details
Main Authors: Abhishek, A, Boyton, RJ, Peckham, N, McKnight, Á, Coates, LC, Bluett, J, Barber, V, Cureton, L, Francis, A, Appelbe, D, Eldridge, L, Julier, P, Valdes, AM, Brooks, T, Rombach, I, Altmann, DM, Nguyen-Van-Tam, JS, Williams, HC, Cook, JA
Other Authors: VROOM study investigators
Format: Journal article
Language:English
Published: Elsevier 2022

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