Piperacillin/tazobactam resistance in a clinical isolate of Escherichia coli due to IS26-mediated amplification of blaTEM-1B.

A phenotype of Escherichia coli and Klebsiella pneumoniae, resistant to piperacillin/tazobactam (TZP) but susceptible to carbapenems and 3rd generation cephalosporins, has emerged. The resistance mechanism associated with this phenotype has been identified as hyperproduction of the β-lacta...

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Bibliographic Details
Main Authors: Hubbard, ATM, Mason, J, Roberts, P, Parry, CM, Corless, C, van Aartsen, J, Howard, A, Bulgasim, I, Fraser, AJ, Adams, ER, Roberts, AP, Edwards, T
Format: Journal article
Language:English
Published: Springer Nature 2020