Living without creatine: Unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice

Living without creatine: Unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice

Diğer sürümleri göster (1)

RATIONALE:: Creatine is thought to be involved in the spatial and temporal buffering of ATP in energetic organs such as heart and skeletal muscle. Creatine depletion affects force generation during maximal stimulation, while reduced levels of myocardial creatine are a hallmark of the failing heart,...

Detaylı Bibliyografya
Asıl Yazarlar:	Lygate, C, Aksentijevic, D, Dawson, D, Ten Hove, M, Phillips, D, De Bono, J, Medway, D, Sebag-Montefiore, L, Hunyor, I, Channon, K, Clarke, K, Zervou, S, Watkins, H, Balaban, R, Neubauer, S
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	2013

Benzer Materyaller

Living without creatine: unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice.
Yazar:: Lygate, C, ve diğerleri
Baskı/Yayın Bilgisi: (2013)

Moderate elevation of intracellular creatine by targeting the creatine transporter protects mice from acute myocardial infarction.
Yazar:: Lygate, C, ve diğerleri
Baskı/Yayın Bilgisi: (2012)

Regulation of Myocardial Creatine Uptake by Intra- and Extracellular Creatine Levels
Yazar:: Makinen, K, ve diğerleri
Baskı/Yayın Bilgisi: (2008)

Elevated Myocardial Creatine Protects Against Ischemia/Reperfusion Injury by Improving Cardiac Energetics
Yazar:: Lygate, C, ve diğerleri
Baskı/Yayın Bilgisi: (2011)

Creatine uptake in mouse hearts with genetically altered creatine levels.
Yazar:: ten Hove, M, ve diğerleri
Baskı/Yayın Bilgisi: (2008)

Chronic creatine kinase deficiency eventually leads to congestive heart failure, but severity is dependent on genetic background, gender and age
Yazar:: Lygate, C, ve diğerleri
Baskı/Yayın Bilgisi: (2012)

Chronic creatine kinase deficiency eventually leads to congestive heart failure, but severity is dependent on genetic background, gender and age.
Yazar:: Lygate, C, ve diğerleri
Baskı/Yayın Bilgisi: (2012)

Adaptations to Maintain Energy Homeostasis Compensate for Creatine-Deficiency in GAMT Knockout Mice Following Myocardial Infarction, but May Contribute to Early Mitochondrial Pathology During Aging
Yazar:: Lygate, C, ve diğerleri
Baskı/Yayın Bilgisi: (2011)

Cardiac phenotype of mitochondrial creatine kinase knockout mice is modified on a pure C57BL/6 genetic background.
Yazar:: Lygate, C, ve diğerleri
Baskı/Yayın Bilgisi: (2009)

Supra-normal (phospho-)creatine levels lead to heart failure in mice overexpressing the cardiac creatine transporter - a longitudinal study
Yazar:: ten Hove, M, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

A role for thioredoxin-interacting protein (Txnip) in cellular creatine homeostasis.
Yazar:: Zervou, S, ve diğerleri
Baskı/Yayın Bilgisi: (2013)

Ribose supplementation alone or with elevated creatine does not preserve high energy nucleotides or cardiac function in the failing mouse heart
Yazar:: Faller, K, ve diğerleri
Baskı/Yayın Bilgisi: (2013)

REGULATION OF CELLULAR CREATINE HOMEOSTASIS: A ROLE FOR THIOREDOXIN INTERACTING PROTEIN (TXNIP)
Yazar:: Zervou, S, ve diğerleri
Baskı/Yayın Bilgisi: (2013)

Changes in creatine transporter function during cardiac maturation in the rat.
Yazar:: Fischer, A, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

Complete absence of creatine but unaltered ATP levels in hearts from AGAT knockout mice
Yazar:: ten Hove, M, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Supernormal myocardial creatine and phosphocreatine concentrations lead to cardiac hypertrophy and heart failure - Insights from creatine transporter over-expression transgenic mice
Yazar:: Wallis, J, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

Unchanged Mitochondrial Organization and Compartmentation in Creatine Deficient GAMT-/- Mouse Heart
Yazar:: Branovets, J, ve diğerleri
Baskı/Yayın Bilgisi: (2013)

Regulation of myocardial creatine uptake capacity in genetically altered mouse models
Yazar:: Ten Hove, M, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Supranormal myocardial creatine and phosphocreatine concentrations lead to cardiac hypertrophy and heart failure: insights from creatine transporter-overexpressing transgenic mice.
Yazar:: Wallis, J, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

Creatine reduces mitochondrial permeability transition pore opening in response to oxidative stress in vitro
Yazar:: Zervou, S, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

Chronic Creatine-deficiency is not the Underlying Cause of Cardiac Dysfunction in Mice Lacking the Creatine Biosynthetic Enzyme Arginine: glycine Amidinotransferase
Yazar:: Lygate, C, ve diğerleri
Baskı/Yayın Bilgisi: (2013)

The creatine kinase energy transport system in the failing mouse heart.
Yazar:: Lygate, C, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Mice over-expressing the myocardial creatine transporter develop progressive heart failure and show decreased glycolytic capacity.
Yazar:: Phillips, D, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

Impaired cardiac contractile function in AGAT knockout mice devoid of creatine is rescued by homoarginine but not creatine
Yazar:: Faller, K, ve diğerleri
Baskı/Yayın Bilgisi: (2017)

Unchanged mitochondrial organization and compartmentation of high-energy phosphates in creatine-deficient GAMT-/- mouse hearts.
Yazar:: Branovets, J, ve diğerleri
Baskı/Yayın Bilgisi: (2013)

The creatine kinase energy transport system in the failing mouse heart
Yazar:: Lygate, C, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

Myocardial creatine levels do not influence response to acute oxidative stress in isolated perfused heart
Yazar:: Aksentijević, D, ve diğerleri
Baskı/Yayın Bilgisi: (2014)

Ribose Supplementation Alone or with Elevated Creatine Does Not Preserve High Energy Nucleotides or Cardiac Function in the Failing Mouse Heart.
Yazar:: Kiterie M E Faller, ve diğerleri
Baskı/Yayın Bilgisi: (2013-01-01)

New insights into the creatine kinase-phosphocreatine energy buffer and transport system using mouse models of altered creatine content
Yazar:: Lygate, C, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

Mechanisms of creatine depletion in chronically failing rat heart.
Yazar:: Ten Hove, M, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

Hearts from gamt ko mice lack phospho-creatine, show reduced inotropic reserve and are more prone to ischemia
Yazar:: ten Hove, M, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

Influence of homoarginine on creatine accumulation and biosynthesis in the mouse
Yazar:: Lygate, CA, ve diğerleri
Baskı/Yayın Bilgisi: (2022)

GUANIDINOACETATE N-METHYLTRANSFERASE KNOCKOUT MICE EXHIBIT NORMAL LEFT VENTRICULAR REMODELLING, HAEMODYNAMICS AND SURVIVAL AFTER MYOCARDIAL INFARCTION DESPITE LACK OF PHOSPHOCREATINE
Yazar:: Lygate, C, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

Influence of homoarginine on creatine accumulation and biosynthesis in the mouse
Yazar:: Craig A. Lygate, ve diğerleri
Baskı/Yayın Bilgisi: (2022-08-01)

Metabolic Inflexibility of Malonyl CoA Decarboxylase (MCD) Knockout Mice Leads to Cardiac Remodelling and High Mortality During Peri-Weaning Period
Yazar:: Aksentijevic, D, ve diğerleri
Baskı/Yayın Bilgisi: (2014)

Myocardial creatine uptake is regulated by the sarcolemmal fraction of the creatine transporter, but not by the total creatine transporter pool
Yazar:: Boehm, E, ve diğerleri
Baskı/Yayın Bilgisi: (2002)

COMPENSATION FOR IMPAIRED MYOCARDIAL PHOSPHOTRANSFER IN GUANIDINOACETATE-N-METHYLTRANSFERASE KNOCKOUT MICE
Yazar:: Aksentijevic, D, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

High-energy phosphotransfer in the failing mouse heart: role of adenylate kinase and glycolytic enzymes.
Yazar:: Aksentijević, D, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

Creatine transporter activity and content in the rat heart supplemented by and depleted of creatine.
Yazar:: Boehm, E, ve diğerleri
Baskı/Yayın Bilgisi: (2003)

The creatine kinase system as a therapeutic target for myocardial ischaemia-reperfusion injury
Yazar:: Cao, F, ve diğerleri
Baskı/Yayın Bilgisi: (2018)