Plexin-semaphorin signaling modifies neuromuscular defects in a drosophila model of peripheral neuropathy
Dominant mutations in GARS, encoding the ubiquitous enzyme glycyl-tRNA synthetase (GlyRS), cause peripheral nerve degeneration and Charcot-Marie-Tooth disease type 2D (CMT2D). This genetic disorder exemplifies a recurring paradigm in neurodegeneration, in which mutations in essential genes cause sel...
| Huvudupphovsmän: | , , |
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| Materialtyp: | Journal article |
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Frontiers Media
2018
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