Interaction of insulin and PPAR-α genes in Alzheimer's disease: the Epistasis Project.

Altered glucose metabolism has been described in Alzheimer's disease (AD). We re-investigated the interaction of the insulin (INS) and the peroxisome proliferator-activated receptor alpha (PPARA) genes in AD risk in the Epistasis Project, including 1,757 AD cases and 6,294 controls. Allele freq...

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Bibliographic Details
Main Authors: Kölsch, H, Lehmann, D, Ibrahim-Verbaas, C, Combarros, O, van Duijn, C, Hammond, N, Belbin, O, Cortina-Borja, M, Lehmann, MG, Aulchenko, Y, Schuur, M, Breteler, M, Wilcock, G, Brown, K, Kehoe, P, Barber, R, Coto, E, Alvarez, V, Deloukas, P, Mateo, I, Maier, W, Morgan, K, Warden, DR, Smith, A, Heun, R
Format: Journal article
Language:English
Published: 2012