Prolonged half-life of verapamil in a case of overdose: implications for therapy.

After an overdose of verapamil (2.4 g) in a 59-year-old man the apparent half-life of verapamil was prolonged (15 h). The most likely mechanism is rate-limiting absorption, although changes in clearance and volume of distribution may contribute. As the elimination half-life of verapamil is increased...

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Bibliographic Details
Main Authors: Buckley, C, Aronson, J
Format: Journal article
Language:English
Published: 1995