Prolonged half-life of verapamil in a case of overdose: implications for therapy.
After an overdose of verapamil (2.4 g) in a 59-year-old man the apparent half-life of verapamil was prolonged (15 h). The most likely mechanism is rate-limiting absorption, although changes in clearance and volume of distribution may contribute. As the elimination half-life of verapamil is increased...
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
1995
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