Assessment of F/HN-pseudotyped lentivirus as a clinically relevant vector for lung gene therapy.

RATIONALE: Ongoing efforts to improve pulmonary gene transfer thereby enabling gene therapy for the treatment of lung diseases, such as cystic fibrosis (CF), has led to the assessment of a lentiviral vector (simian immunodeficiency virus [SIV]) pseudotyped with the Sendai virus envelope proteins F a...

ver descrição completa

Detalhes bibliográficos
Principais autores: Griesenbach, U, Inoue, M, Meng, C, Farley, R, Chan, M, Newman, N, Brum, A, You, J, Kerton, A, Shoemark, A, Boyd, A, Davies, J, Higgins, T, Gill, DR, Hyde, S, Innes, J, Porteous, D, Hasegawa, M, Alton, E
Formato: Journal article
Idioma:English
Publicado em: 2012