Epimerization of C5 of an N-hydroxypyrrolidine in the synthesis of swainsonine related iminosugars
Epimerization of C5 of an N-hydroxypyrrolidine ring by regioselective oxidation to a nitrone followed by diastereoselective reduction provides a newapproachto the synthesis of swainsonine and related compounds. The only protection in the synthesis of the potent mannosidase inhibitor DIM (1, 4-dideox...
| Hlavní autoři: | , , , , , , |
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| Médium: | Journal article |
| Vydáno: |
Royal Society of Chemistry
2016
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