Epimerization of C5 of an N-hydroxypyrrolidine in the synthesis of swainsonine related iminosugars
Epimerization of C5 of an N-hydroxypyrrolidine ring by regioselective oxidation to a nitrone followed by diastereoselective reduction provides a newapproachto the synthesis of swainsonine and related compounds. The only protection in the synthesis of the potent mannosidase inhibitor DIM (1, 4-dideox...
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Bibliographic Details
| Main Authors: |
Qian, B,
Kamori, A,
Kinami, K,
Kato, A,
Li, Y,
Fleet, G,
Yu, C |
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| Format: | Journal article
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| Published: |
Royal Society of Chemistry
2016
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