Inhibition of hemangiogenesis and lymphangiogenesis after normal-risk corneal transplantation by neutralizing VEGF promotes graft survival.

PURPOSE: To evaluate the occurrence and time course of hem- and lymphangiogenesis after normal-risk corneal transplantation in the mouse model and to test whether pharmacologic strategies inhibiting both processes improve long-term graft survival. METHODS: Normal-risk allogeneic (C57BL/6 to BALB/c)...

Full description

Bibliographic Details
Main Authors: Cursiefen, C, Cao, J, Chen, L, Liu, Y, Maruyama, K, Jackson, D, Kruse, F, Wiegand, S, Dana, MR, Streilein, J
Format: Journal article
Language:English
Published: 2004