Direct specification of lymphatic endothelium from mesenchymal progenitors

During embryogenesis, endothelial cells (ECs) are generally described to arise from a common pool of progenitors termed angioblasts, which diversify through iterative steps of differentiation to form functionally distinct subtypes of ECs. A key example is the formation of lymphatic ECs (LECs), which...

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Bibliographic Details
Main Authors: Lupu, I, Grainger, DE, Kirschnick, N, Weischer, S, Zhao, E, Martinez-Corral, I, Schoofs, H, Vanhollebeke, M, Jones, G, Godwin, J, Forrow, A, Lahmann, I, Riley, PR, Zobel, T, Alitalo, K, Mäkinen, T, Kiefer, F, Stone, OA
Format: Journal article
Language:English
Published: Springer Nature [academic journals on nature.com] 2025