Design and synthesis of haptens for the catalytic antibody-promoted dynamic kinetic resolution of oxazolin-5-ones
The synthesis of the first two haptens designed to elicit catalytic hydrolytic antibodies for the dynamic kinetic resolution of racemic 4-substituted 4H-oxazolin-5-ones is reported. A cyclic phosphinate and a 2,5-dihydro-1H-pyrrolium derivative were chosen as "first generation" haptens. Th...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
2002
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