Endothelial cell tetrahydrobiopterin deficiency attenuates LPS-induced vascular dysfunction and hypotension

Overproduction of nitric oxide (NO) is thought to be a key mediator of the vascular dysfunction and severe hypotension in patients with endotoxaemia and septic shock. The contribution of NO produced directly in the vasculature by endothelial cells to the hypotension seen in these conditions, vs. the...

Повний опис

Бібліографічні деталі
Автори: Chuaiphichai, S, Starr, A, Nandi, M, Channon, K, McNeill, E
Формат: Journal article
Мова:English
Опубліковано: Elsevier 2015