Endothelial cell tetrahydrobiopterin deficiency attenuates LPS-induced vascular dysfunction and hypotension

Endothelial cell tetrahydrobiopterin deficiency attenuates LPS-induced vascular dysfunction and hypotension

Overproduction of nitric oxide (NO) is thought to be a key mediator of the vascular dysfunction and severe hypotension in patients with endotoxaemia and septic shock. The contribution of NO produced directly in the vasculature by endothelial cells to the hypotension seen in these conditions, vs. the...

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Bibliografiske detaljer
Main Authors:	Chuaiphichai, S, Starr, A, Nandi, M, Channon, K, McNeill, E
Format:	Journal article
Sprog:	English
Udgivet:	Elsevier 2015

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