Endothelial cell tetrahydrobiopterin deficiency attenuates LPS-induced vascular dysfunction and hypotension

Overproduction of nitric oxide (NO) is thought to be a key mediator of the vascular dysfunction and severe hypotension in patients with endotoxaemia and septic shock. The contribution of NO produced directly in the vasculature by endothelial cells to the hypotension seen in these conditions, vs. the...

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Những tác giả chính: Chuaiphichai, S, Starr, A, Nandi, M, Channon, K, McNeill, E
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Elsevier 2015