Population pharmacokinetic and pharmacodynamic properties of intramuscular quinine in Tanzanian children with severe Falciparum malaria.

Although artesunate is clearly superior, parenteral quinine is still used widely for the treatment of severe malaria. A loading-dose regimen has been recommended for 30 years but is still often not used. A population pharmacokinetic study was conducted with 75 Tanzanian children aged 4 months to 8 y...

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Bibliographic Details
Main Authors: Hendriksen, I, Maiga, D, Lemnge, M, Mtove, G, Gesase, S, Reyburn, H, Lindegardh, N, Day, N, Von Seidlein, L, Dondorp, A, Tarning, J, White, N
Format: Journal article
Language:English
Published: 2013