A polymorphism in human CD1A is associated with susceptibility to tuberculosis

CD1 proteins are antigen-presenting molecules that evolved to present lipids rather than peptides to T cells. However, unlike major histocompatibility complex genes, CD1 genes show low rates of polymorphism and have not been clearly associated with human disease. We report that an intronic polymorph...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Seshadri, C, Thuong, N, Yen, N, Bang, N, Chau, T, Thwaites, G, Dunstan, S, Hawn, T
Format: Journal article
Język:English
Wydane: Nature Publishing Group 2014