A polymorphism in human CD1A is associated with susceptibility to tuberculosis

CD1 proteins are antigen-presenting molecules that evolved to present lipids rather than peptides to T cells. However, unlike major histocompatibility complex genes, CD1 genes show low rates of polymorphism and have not been clearly associated with human disease. We report that an intronic polymorph...

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Main Authors: Seshadri, C, Thuong, N, Yen, N, Bang, N, Chau, T, Thwaites, G, Dunstan, S, Hawn, T
格式: Journal article
语言:English
出版: Nature Publishing Group 2014