Functional heterogeneity and high frequencies of cytomegalovirus-specific CD8(+) T lymphocytes in healthy seropositive donors.

Human cytomegalovirus (HCMV) infection is largely asymptomatic in the immunocompetent host, but remains a major cause of morbidity in immunosuppressed individuals. Using the recently described technique of staining antigen-specific CD8(+) T cells with peptide-HLA tetrameric complexes, we have demons...

全面介绍

书目详细资料
Main Authors: Gillespie, G, Wills, MR, Appay, V, O'Callaghan, C, Murphy, M, Smith, N, Sissons, P, Rowland-Jones, S, Bell, J, Moss, P
格式: Journal article
语言:English
出版: 2000