c-Myb and GATA-1 alternate dominant roles during megakaryocyte differentiation.

c-Myb and GATA-1 alternate dominant roles during megakaryocyte differentiation.

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BACKGROUND: Transcription factors are essential for blood cell formation. Mice expressing low levels of c-Myb (c-Myb(low)) have an increased number of bone marrow megakaryocytes (MKs) and corresponding thrombocytosis. In contrast, mice engineered to express low levels of GATA-1 (GATA-1(low)) in the...

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मुख्य लेखकों: García, P, Berlanga, O, Vegiopoulos, A, Vyas, P, Frampton, J
स्वरूप: Journal article
भाषा:English
प्रकाशित: 2011
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