SDR-type human hydroxysteroid dehydrogenases involved in steroid hormone activation.

Hydroxysteroid dehydrogenases catalyze the NAD(P)(H)-dependent oxidoreduction of hydroxyl and oxo-functions at distinct positions of steroid hormones. This reversible reaction constitutes an important pre-receptor control mechanism for nuclear receptor ligands of the androgen, estrogen and glucocort...

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Váldodahkkit: Wu, X, Lukacik, P, Kavanagh, K, Oppermann, U
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 2007