SDR-type human hydroxysteroid dehydrogenases involved in steroid hormone activation.

Hydroxysteroid dehydrogenases catalyze the NAD(P)(H)-dependent oxidoreduction of hydroxyl and oxo-functions at distinct positions of steroid hormones. This reversible reaction constitutes an important pre-receptor control mechanism for nuclear receptor ligands of the androgen, estrogen and glucocort...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Wu, X, Lukacik, P, Kavanagh, K, Oppermann, U
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2007