IRF5:RelA interaction targets inflammatory genes in macrophages.

Interferon Regulatory Factor 5 (IRF5) plays a major role in setting up an inflammatory macrophage phenotype, but the molecular basis of its transcriptional activity is not fully understood. In this study, we conduct a comprehensive genome-wide analysis of IRF5 recruitment in macrophages stimulated w...

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Bibliographic Details
Main Authors: Saliba, D, Heger, A, Eames, H, Oikonomopoulos, S, Teixeira, A, Blazek, K, Androulidaki, A, Wong, D, Goh, F, Weiss, M, Byrne, A, Pasparakis, M, Ragoussis, J, Udalova, I
Format: Journal article
Language:English
Published: 2014