Differential corticospinal tract degeneration in homozygous 'D90A' SOD-1 ALS and sporadic ALS.

Differential corticospinal tract degeneration in homozygous 'D90A' SOD-1 ALS and sporadic ALS.

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BACKGROUND: The homogeneous genotype and stereotyped phenotype of a unique familial form of amyotrophic lateral sclerosis (ALS) (patients homozygous for aspartate-to-alanine mutations in codon 90 (homD90A) superoxide dismutase 1) provides an ideal model for studying genotype/phenotype interactions a...

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Main Authors: Blain, C, Brunton, S, Williams, VC, Leemans, A, Turner, MR, Andersen, P, Catani, M, Stanton, B, Ganesalingham, J, Jones, D, Williams, S, Leigh, P, Simmons, A
פורמט: Journal article
שפה:English
יצא לאור: 2011

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