GenomegaMap: Within-species genome-wide dN/dS estimation from over 10,000 genomes

The dN/dS ratio provides evidence of adaptation or functional constraint in protein-coding genes by quantifying the relative excess or deficit of amino acid-replacing versus silent nucleotide variation. Inexpensive sequencing promises a better understanding of parameters, such as dN/dS⁠, but analyzi...

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Bibliographic Details
Main Authors: Wilson, DJ, Crook, DW, Peto, TEA, Walker, AS, Hoosdally, S, Gibertoni Cruz, AL, Carter, J, Grazian, C, Earle, SG, Kouchaki, S, Lachapelle, A, Yang, Y, Clifton, DA, Fowler, PW
Other Authors: CRyPTIC Consortium
Format: Journal article
Language:English
Published: Oxford University Press 2020